The massive use of digital and information technologies in everyday life and in cultural production has reached a new dimension with the emergence of the covid-19 pandemic and has further stimulated significant changes in habits of living and communication in the contemporary media ecology. This text examines the effects of interaction with digital media on the level of the experience of art in perceptual and cognitive terms. It highlights analyses of media interaction in the fields of neuroscience, experimental aesthetics and cognitive science, and explores the processes of experiencing digitally mediated artworks based on the mediation of the screen and other interactive interfaces in contemporary media art. It highlights the differences in the experience of the process of artistic creation in digital or analogue media and the changes in the aesthetic-sensory responsiveness to the original work of art or its digital reproduction. While we are witnessing a constant remediation of our mind, technological media research is focusing on the processes of fusion and feedback of neural and media processes described by the concept of neuromediality.
